In a new study, researchers discovered that pharmaceutical opioids produce their effects by binding to receptors inside neurons; this is contrary to previous theories that these drugs acted only on the same surface receptors as the body’s natural endogenous opioids.
This difference between how medically used and naturally made opioids interact with nerve cells may help guide the development of pain relievers that do not lead to addiction or other negative effects produced by opioid...
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source https://psychcentral.com/news/2018/05/13/opioid-meds-act-on-different-receptors-than-bodys-opioids/135325.html
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